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| Passive | Aegis Protection | | | | After attacking or casting spells 4 times, Pantheon will block the next incoming basic attack or turret attack. |
| Q | Spear Shot | | 45 / 45 / 45 / 45 / 45 Mana | 4 / 4 / 4 / 4 / 4 | Pantheon hurls his spear at an opponent, dealing 65/105/145/185/225 (+) physical damage. |
| W | Aegis of Zeonia | | 55 / 55 / 55 / 55 / 55 Mana | 13 / 12 / 11 / 10 / 9 | Pantheon leaps at the target enemy champion, minion or neutral monster and deals 50/75/100/125/150 (+1) magic damage and stuns them for 1/1/1/1/1 second(s). Pantheon also instantly refreshes his Aegis Protection. |
| E | Heartseeker Strike | | 45 / 50 / 55 / 60 / 65 Mana | 10 / 9 / 8 / 7 / 6 | Passive: Pantheon's basic attacks and Spear Shot gain 100% critical strike chance against targets below 15/15/15/15/15% health.
Active: Pantheon focuses and deals 3/3/3/3/3 swift strikes in front of him for 13/23/33/43/53 (+) physical damage per strike. Deals double damage to champions. |
| R | Grand Skyfall | | 125 / 125 / 125 Mana | 150 / 135 / 120 | Pantheon gathers his strength and then leaps high into the air, crashing down at the target area a few seconds later. Deals up to 400/700/1000 (+1) magic damage to units at the center (down to 50/50/50% at the edge) and slows their Movement Speed by 35/35/35% for 1 second. |